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Adverse effects are the main limitations of this class of medications and include somnolence and anticholinergic effects

IL-18, Interleukin-18

The main mechanism is that paracetamol may impair respiratory antioxidant defences by decreasing the amount of reduced glutathione present

One key enzyme in this complex system known as glutathione peroxidase (GPx) for example can react almost 200x faster than other food-based antioxidants and is more specific for targeting chronic stress

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