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5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), the cytosolic enzyme that methylates nicotinamide to 1-methylnicotinamide (1-MNA) using S-adenosyl-L-methionine (SAM) as the methyl donor

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B12 supplements may reduce fatigue and improve endurance, making them popular among athletes and individuals with busy lifestyles

By inhibiting the NNMT enzyme, 5-Amino-1MQ supports reduced fat storage and enhanced energy metabolism