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2021 Apr 30
A decrease in tumour volume of at least 50% was classified as regression, an increase in tumour volume of at least 35% identified progressive disease and volume changes between +35% and 50% were considered as stable disease 54
In addition, H 2 O 2 affects the antioxidant system, as indicated by the levels of GPX4, GSH and RSH in cells significantly increasing upon exposure to high levels of H 2 O 2 , which may lead to an imbalance in redox homeostasis and eventually trigger oxidative stress [63]
They cause oxidative stress when left unchecked, which damages cell membranes, DNA and proteins
Changes in brain GSH levels over time were determined as the difference between the GSH/Cr ratio (or absolute GSH) at each time point, relative to baseline
