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9,32 However, it also affects the retention time of drugs in the nasal mucosa, directly influencing the success of nose-to-brain drug delivery

IV infusions bypass that issue but require time, cost, and access to a clinic
In light of this, the use of immunocompetent mice models, such as genetically engineered (GEM) or syngeneically transplanted models would enhance the ability to effectively represent MET-mediated cellular behaviours

Clin Chem Lab Med 36 : 215222
Novel GLP-1-based Medications for Type 2 Diabetes and Obesity (Endocrine Reviews)
