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To date, eleven gene loci labeled PARK111, DJ-1, Parkin, leucine-rich repeat kinase 2 (LRRK2), ubiquitin carboxyterminal hydrolase-L1 (Uch-L1), -synuclein and PINK1 have been characterized according to their function and cellular localization (reviewed in [324, 325])

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Recent studies have proved that some traditional medicine could suppress the progression of UC models by inhibiting inflammatory cell infiltration and the production of pro-inflammatory cytokines