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Subcellular fractions, such as vesicles, nuclei, lysosomes, and microsomes, can be used to study subcellular distribution, the interaction between a cellular compartment and a chemical, and the kinetics of binding or release of substances
Another important signalling molecule related to SIRT1 is the AMP-activated protein kinase (AMPK), which acts as an initial sensor to increase the level of NAD + [346]
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[DOI] [PubMed] [Google Scholar] 31.Noller HF, Hoffarth V, Zimniak L
