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Yet, a consensus regarding the model in which UPR mt plays a causal role is still elusive

doi: 10.3389/fphar.2025.1543575, 190

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6 g twice daily) for six months (94), required less additional therapy and had improved bronchial hyperreactivity with a reduction in eosinophil count and total IgE, IL-4, IL-5, TNF-, and airway inflammatory lipid mediators such as Cys-LT, LTb4 and 8-isoprostanes with no significant changes in IL-10 and IFN-, compared to the group with standard pharmacotherpay alone (94)

Still, for a fast answer, the best way to avoid lumpy clumping whey is to slowly add your dry whey into a minimal amount of solvent (liquid) and mix the resulting solution into a uniform paste free of lumps