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4-Methylpyrazole protects against acetaminophen hepatotoxicity in mice and in primary human hepatocytes

NOX2, also known as the phagocyte NADPH oxidase, is the prototypical NOX and has a distinct role in the host defence against bacteria, where NOX2 in phagosomes generates superoxide to kill bacteria

Blackmon SH, Stephens EH, Correa AM, Hofstetter W, Kim MP, Mehran RJ, Rice DC , Roth JA, Swisher SG, Walsh GL, Vaporciyan AA
16(6): e0252476

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