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Critics contend that TMAO's broad associations with inflammation, thrombosis, atherogenesis, and renal function are overstated, proposing instead that elevated levels may simply reflect impaired renal clearance or other underlying disease statesessentially acting as an expensive replacement for creatinine or eGFR testing

Mu J, Xu J, Wang L, Chen C, Chen P

Since free CoA and L-carnitine react in a 1:1 molar ratio, the L-carnitine content in the sample can be determined indirectly

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