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High BLT2 expression is observed in human lung adenocarcinomas with KRAS mutations, whereas BLT2 inhibition, either pharmacologically or through genetic knockout, decreases lung tumor formation, IL-6 production, and airway inflammation in KRAS-mutant mouse models [136]

The effect of oxidative stress and antioxidant enzymes on the macrophage function and M1 and M2 polarisation during skeletal muscle regeneration has not been investigated yet

Shaw LT, Mackin A, Shah R, Jain S, Jain P, Nayak R et al (2020) Risuteganiba novel integrin inhibitor for the treatment of non-exudative (dry) age-related macular degeneration and diabetic macular edema