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Wang S, Yuan Y-H, Chen N-H, Wang H-B (2019) The mechanisms of NLRP3 inflammasome/pyroptosis activation and their role in Parkinsons disease

This is considered a favorable alternative to orally bioavailable PDE5 inhibitors that show poor results in subjects with acute metabolic disease [10, 15, 16]
An example of an approved therapy is Venetoclax, a BCL2 inhibitor which has demonstrated efficacy as a monotherapy or in combination regimens for treating chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and acute myeloid leukemia (AML) (1517)

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H., Harris, R
