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Targeting these cytokines or their downstream signaling pathways offers a strategy to disrupt the self-perpetuating loop linking ferroptotic cell death to fibroblast activation and ECM deposition
Cellular repair networks linking oxidative defense, collagen synthesis, and immune modulation
68 Most recent reviews assume that NAC functions as an excellent scavenger of all ROS generated during oxidative stress and, thus, protects the GSH stores
Arthritis Rheum (2008) 58:387383
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