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The formation of AGEs leads to the crosslinking and aggregation of proteins contributing to lens aging and cataract formation

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34 Enzymes such as CAT, SOD, and GPx are important components of the bodys antioxidant defense system

Among these genes, some of them are associated with alterations of free radical formation or mitochondrial dysfunctions

The resulting extracts were profiled on an accurate mass global metabolomics platform consisting of multiple arms differing by chromatography methods and MS ionization modes to achieve broad coverage of compounds differing by physiochemical properties such as mass, charge, chromatography separation and ionization behaviour