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Immunosenescence contributes to: At the same time , many older adults experience "inflammaging," a state of persistent low-grade inflammation that accelerates biological aging

Evidence suggests that abnormal lipid metabolism is frequently observed in autoimmune diseases, underscoring its potential involvement in disease development

Inhibition of FABP5, in human or murine Treg, either pharmacologically or through genetic elimination, leads to loss of mitochondrial structure and a reduction in fatty metabolism, both of which together compromise Treg suppressive capacity (151)

Ann Thorac Surg 107(3):936-940, 2019

Cancer Cell 33 , 690705.e9 (2018)
