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were able to activate holo-Grx2 using a xanthine/xanthine oxidase system indicating O 2 may be responsible for 2Fe-2S cluster disassembly (Gao et al., 2013)
Although CAT and GPX share common substrates, compared to GPX, CAT has been reported to have a lower affinity for H 2 O 2 at low concentrations (i.e., GPX K m = 1M vs
Overall these results suggest that GSH can bind to capsid intermediates under normal conditions
Prx6 directly binds selenide or selenol intermediates at its catalytic cysteine 47 in the presence of GSH
Khoury JD, et al
