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Additionally, IPA functions as an allosteric inhibitor of TrpE by mimicking tryptophan, blocking the catalytic step of tryptophan synthesis mediated by TrpE, thus disrupting metabolic pathways in pathogens such as Mycobacterium tuberculosis and suppressing their proliferation (91)
Jiang Y, Almannai M, Sutton VR, Sun Q, Elsea SH
Identification of Novel Filament-Forming Proteins in Saccharomyces Cerevisiae and Drosophila Melanogaster
Antioxidant metabolism of Xenopus leavis embryos the first days of development
Vindas et al., 2017)
