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Similar content being viewed by others Introduction The presence of the blood-brain barrier (BBB), a tightly interconnected network of blood vessels and endothelial cells that restricts the entry of foreign particles larger than 100 nm into the brain, poses considerable challenges and complexities in advancing therapeutic strategies for neurodegenerative diseases (NDs) 1
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Adv Drug Deliv Rev 160:1935 McCright J, Skeen C, Yarmovsky J, Maisel K (2022) Nanoparticles with dense poly (ethylene glycol) coatings with near neutral charge are maximally transported across lymphatics and to the lymph nodes

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