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The TMAO levels are also elevated in patients with chronic HF, correlating with the functional class and diastolic dysfunction, but not systolic dysfunction, suggesting that increased venous congestion associated with backward failure may significantly alter the gut microbiota (GMB) to promote TMAO production
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J2 was isolated from acclimated activated sludge [454]
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Furthermore, MOTS-c has been extensively investigated for its potential to enhance mitochondrial function itself
