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Tepotinib: first approval

Bauca, J

Hepatocyte-specific mutation establishes retinoid X receptor a as a heterodimeric integrator of multiple physiological processes in the liver

These compounds are small, skin-loving molecules that signal collagen production and repair

In brief, hPSCs were plated at a density of 5000 cells/well in a 24-well plate in mTeSR1 medium (Stem Cell Technologies, Vancouver, BC, Canada) + 10 M Y27632 (LC Laboratories, Woodburn, MA) on glass plates (LabTek) coated with 3% GelTrex (Thermo Fisher Scientific, USA) (Day-3)