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For a review of the achievements and implementation of the EURL ECVAM strategy plan read Corvi and Madia, 2017

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Symptoms may persist after removal of the transdermal system [see Warnings and Precautions (5.5)]

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Activation of these receptors in the brain (particularly brainstem and hypothalamic regions) suppresses appetite, reduces food intake through both homeostatic and hedonic pathways, slows gastric emptying to prolong fullness, and inhibits postprandial glucagon release to aid glucose control

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doi: 10.2217/nnm-2022-0287 183 NarayanS.GuptaP

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