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Vitamin B12 deficiency associated with histamine2-receptor antagonists and a proton-pump inhibitor

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Both medications require refrigeration until first use, then remain stable at room temperature for a defined period (typically 21 to 56 days depending on specific product)

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Sources Vitamin B12 can be obtained from animal-derived foods such as meat, poultry, fish, dairy items, and eggs

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Endocrine (2016) 52:6529

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This combination has been associated with improved functional activity of the lymphoid system and changes in blood system homeostasis in the studied subjects

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