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4-Hydroxy-L-glutamate is a substrate for deamination by aspartate transaminase (AST) which uses 2-oxoglutarate (-ketoglutarate) as the amino acceptor, generating 4-hydroxy-2-oxoglutarate and glutamate

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Animal studies have found that the production of telomerase indicates that the Epithalon peptide offers a range of benefits, including improved sleep quality, enhanced mood, and potent antioxidant effects that help neutralize harmful free radicals

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It can neutralize free radicals, reduce oxidative stress, and act as a detoxifying agent