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Thus, the enzymatic reduction of roGFP2(S 2 ) by GSH follows monothiol mechanism (iii) and requires a glutaredoxin to form roGFP2(SSG)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 224.Eslami A.C., Pasanphan W., Wagner B.A., Buettner G.R

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[81] compared 68 Ga and 18 F, demonstrating that 68 Ga is a more effective CR-PDT radionuclide

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when this process is compromised, Fe + activates lipid peroxidases, producing reactive oxygen species (50), which oxidize membrane polyunsaturated fatty acids (PUFAs) to PUFA-OOHs, resulting in irreversible membrane damage and cellular apoptosis ( Figure 4 )

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