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Without this ISC, its enzymatic activity is compromised

Hah et al

Matsuda M, Gono T, Morita H, Katoh N, Kodaira M, Ikeda S

It helps reduce dullness, supports a more even-looking skin tone, and promotes that natural healthy glow people actually notice

The transdermal composition of claim 2 wherein polymer is selected from one or more of polyethylene glycol, methacrylate copolymers (Eudragits), Acrylic copolymer, Polyster Film/copolymer of ethylene and vinyl acetate, Poly (Butyl methacrylate, methyl methacrylate), cellulose polymers (carboxymethylcellulose, ethyl cellulose, hydroxypropylmethylcellulose hydroxypropylcellulose), polyvinylpyrrolidone, polymer of acrylic acid crosslinked with allyl ethers of polyalcohols (carbomer / carbopol)