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Another possible regulatory pathway of P450 by cannabinoids involves indirect influence on the noradrenergic and serotonergic transmission in specific brain regions, such as the locus coeruleus (major noradrenergic brainstem nucleus) and the dorsal raphe nuclei (the largest serotonergic nucleus) (Michelsen et al., 2008

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Effects of diclofenac, L-NAME, L-arginine, and pentadecapeptide BPC 157 on gastrointestinal, liver, and brain lesions, failed anastomosis, and intestinal adaptation deterioration in 24 hour-short-bowel rats

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