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However, in addition to the advanced instrumentation and analytical techniques, the quality and behavior of the biological samples remain crucial for successful structure determination using both methods, with flexibility and conformational dynamics being the usual reasons for decreasing resolution

reported that low dosage of curcumin (160 ppm) administered orally for 6 months reduced both the insoluble amyloid and A plaque burden in APPSw brain respectively by 39% and 43.6%, which were consistent with previous observation in ibuprofen-treated animals [41]

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The reaction was quenched by adding 8 L of 5% hydroxylamine to the labeled samples and were incubated for 30 minutes at RT

[Google Scholar] Saruhan N, Terzi R, Saglam A, Kadioglu A