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To address the issue of cytotoxicity, the delivery of bevacizumab mRNA via poly (beta-amino ester) (PBAE) nanoparticles targeted to the lungs has demonstrated a more pronounced inhibitory effect on tumor proliferation and angiogenesis in a murine model of orthotopic non-small cell lung cancer (NSCLC)

International Journal of Applied Research in Natural Products , 4 (1), 3743

& Barros, A

Isolation of mitochondria Crude mitochondria from adipose tissue were obtained as described by Wieckowski et al

The mechanisms underlying neurological disorders are complex, and oxidative stress is recognized as a critical regulatory factor, making it a focus of current research [178,179]