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5-Amino-1MQ, by contrast, works over a longer arc: NNMT inhibition builds gradually over days to weeks, with NAD+ levels peaking after consistent daily dosing for 710 days

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3.2 Peptide-triggered pyroptosis in prostate cancer cells Pyroptosis stands out as another remarkable form of ICD, adept at potently activating the antitumor immune response (Loveless et al., 2021)