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Support healthy liver metabolism of estrogens, detoxification, and elimination with DIM+13C

[DOI] [PMC free article] [PubMed] [Google Scholar] 127.Yuan S., Chen J., Dan L., Xie Y., Sun Y., Li X., Larsson S.C

The involvement of efflux proteins is known to be one of the major factors influencing the therapeutic efficacy of drugs, and this is no different in the case of PROTACs

The primary antibodies include Glutamate cysteine ligase catalytic and modifier subunits (GCLC, GCLM), Glutathione Synthetase (GSS), Peroxisome proliferator-activated receptor-gamma coactivator (PGC)1alpha (PGC1), mitochondrial complexes I-V, mitochondrial adenosine triphosphate (ATP) synthase F1 subunit alpha (ATP5A), Phosphate and tensin homolog (PTEN)-induced kinase 1 (PINK1)

The human CHAC2 protein predates CHAC1, with the two sharing only 50% sequence identity (Nguyen et al., 2020)
