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A wide range of mushroom species, including Ganoderma lucidum has demonstrated in vitro potential to protect from Herpes simplex virus (HSV) due to the presence of anti-viral bioactive compounds, including its triterpenoids (especially ganoderic acid B and C1) and polysaccharides, which possess the ability to fight against this virus (61)

Cellular iron accumulation can promote BCL6 gene hydroxymethylation by enhancing Fe2+-dependent TET enzyme activity in TFH cells, thereby promoting TFH cell differentiation (147)

Single-cell transcriptomics revealed a skin-imprinted trajectory of inflammatory eosinophils that strongly expressed the glucose transporter Slc2a3 (GLUT3) These eosinophils impeded the function of Th1 cells by forming a competitive metabolic niche through preferential glucose uptake

Structure of the molecule and their specificity towards enzymes is crucial to evaluate the stability of protein and peptide drugs (Bernkop-Schnurch, 1998)