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The development of artificial Moschus berezovskii can be described as a sword sharpened for decades, which has completely solved the problem of long-term shortage of Moschus berezovskii supply (Fu et al., 2023)

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Composed of 15 amino acids, this pentadecapeptide has been shown in research to stimulate angiogenesis, collagen formation, and tissue remodeling.- It may interact with nitric oxide pathways, growth factor expression, and inflammatory cascades to support endothelial function and cellular recovery.- Suggested mechanisms include upregulation of VEGF, engagement with FAK-paxillin signaling, and protective effects under oxidative stress conditions

A model of persistent circulating IL-12 but without direct injury to the brain or BBB demonstrated elevated TNF- and IFN- within the circulation and brain (Hu et al., 2021)

Yet, the number of knee cartilage repair and regeneration procedures performed annually is dwarfed by the volume of total knee replacements