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[DOI] [PubMed] [PMC] Chu MJ, Phillips AR, Hosking AW, MacDonald JR, Bartlett AS, Hickey AJ

Within the tumor microenvironment, cancer cell-derived exosomes protect stromal cells from ferroptosis and contribute to stromal cell reprogramming (phenotypic alterations), immunosuppression, and metabolic remodelingprocesses that favor cancer progression

doi: 10.1007/s00125-013-2955-4 52 GambleAPepperARBruniAShapiroAMJ

It follows an autosomal dominant inheritance pattern with prevalence ranging from 1 in 12,000 to 1 in 50,000 [151]
