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Description
Here, we report on such a dual engineering approach, where the REW substitutions in IgG1 resulted in favorable pharmacokinetics in human FcRn expressing mice, combined with increased ability to activate the classical complement pathway in an on-target manner

"Wellness is not about a single magic pill

N-acetylcysteine ( NAC) and alpha lipoic acid (ALA) are also used to increase GSH levels

doi: 10.1186/s13052-020-0782-z

Other parameters like growth velocity (in children), body composition, bone density, or general well-being can help assess effectiveness
