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Eventually, these changes lead to inflammation and migraine attacks (202, 203)

Relief of ovalbumin-induced airway remodeling by the glycyl-l-histidyl-l-lysine-Cu2+ tripeptide complex via activation of SIRT1 in airway epithelial cells

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This inflammation may impact DAO production or activity, worsening histamine intolerance in those with already low DAO levels

140 , 186 , 187 , 188 , 189 , 190 , 191 , 192 , 193 , 194 , 195 , 196 For example, a study of more than 39,000 individuals from 13 longitudinal studies of aging found associations between good social connections (e.g., frequent contact with family and friends, having a confidante or never feeling lonely) and lower risk of dementia
