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In normal physiologic state, the brain parenchyma is only subject to nascent immune surveillance, however during inflammation, the elevated pro-inflammatory markers induce the increased expression of adhesion molecules like intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) on the endothelial cells of the BBB (Varatharaj and Galea, 2017
**Quality and Purity Standards** This GHK-Cu research peptide is manufactured under GMP conditions using solid-phase peptide synthesis and purified via HPLC to achieve 99% HPLC purity
doi: 10.1002/1878-0261.12851
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