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Gut microbiota-derived trimethylamine N-oxide is associated with the risk of all-cause and cardiovascular mortality in patients with chronic kidney disease: a systematic review and dose-response meta-analysis
However, a recent study has shown that in order to lethally impact the peroxidation process, PUFAs must be activated and integrated into phospholipids (PLs), a form of membrane lipid, and that free fatty acids cannot trigger ferroptosis

[3] Mitochondrial decay and oxidative damage to RNA/DNA increases with age in the rat hippocampus, a region of the brain associated with memory

However, it encounters several limitations

Anchour et al
