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This plug may cause the follicle wall to bulge and produce a whitehead or, the plug may be open to the surface and may darken, causing a blackhead

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The significant prevalence of depression in patients with acquired hypothyroidism, coupled with the high susceptibility to developing depression and anxiety, highlights the need for enhanced monitoring of psychiatric symptoms

However, in the present study, the difference in the effects of the two carnitine isomers on muscle metabolism was less marked