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Conclusions Changes in intra-portal insulin levels play an intricate yet permissive role in the regulation of the GH/IGF-I axis by either stimulating or suppressing hepatic GH sensitivity and hepatic IGF-I generation, probably via an insulin-mediated regulation of the hepatic GHR expression

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Combined with global data sharing and AI, this will create a self-improving analytical ecosystem one that continuously refines theoretical and experimental harmony
