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Description
Interferon- (IFN-) predominantly acts through the JAK1/2-STAT1 pathway to induce M1 polarization, enhancing the expression of other proinflammatory factors such as IL-6 and tumor necrosis factor- (TNF-), with TNF- being a potent promoter of M1 polarization as well as a significant inhibitor of M2 polarization [47]

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Frequency: Every 1 to 3 months, depending on blood test results and physician recommendations

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