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and the hemibiotrophic pathogen Magnaporthe oryzae identified a significant increase in proteins related to oxidative stress

Its metabolism has been extensively studied and reviewed (Kensler et al

10.14218/JCTH.2015.00052 61 ZhangM.TangZ
Your body doesnt always convert it wellespecially if you have a genetic variation in an enzyme called DHFR (dihydrofolate reductase)