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As highlighted in a recent review, tissue senescent cell abundance obtained under similar conditions may vary up to ten-fold across different studies and experimental techniques

Glutathione acts as a specialized guard for the mitochondria, cleaning up the metabolic byproducts of energy production

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In the presence of bound Wnt ligands, degradation is prevented and -catenin is free to translocate to the nucleus and combine with transcription factors TCF/LEF to initiate the transcription of Wnt target genes (Logan and Nusse, 2004)

Epithelial cells and their neighbors