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M., Chaudhary N., et al

As a note, -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/kainate receptors are important for the initial stages of remyelination after experimentally induced demyelination, where the binding of glutamate released from active axons within the lesion promotes proliferation, survival and differentiation of OPCs during development and adulthood in rodents (Gautier et al., 2015

Chen et al., 2006

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It uses a synthetic peptide corresponding to the final 24 C-terminal residues of the E-domain variously written as MGF-Ct24E, MGF-24aa-E, or simply the MGF peptide. This distinction is critical and frequently blurred: when the literature reports that MGF activates satellite cells or promotes myoblast proliferation, it is almost always referring to this isolated E-domain peptide, not to the intact spliced protein that carries a functional IGF-1 core