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A long-lasting, antigen-specific memory T cell response was generated in a TB murine model when bergenin was co-treated with INH, and the immune damage and bacterial load of mice were significantly reduced and the treatment duration was shortened remarkably (Kumar S

Piperine may also interfere with efflux drug transporters and phase I cytochrome P450 enzymes and increase the bioavailability and slow the elimination of a number of drugs, including phenytoin (Dilantin), propranolol (Inderal), theophylline, and carbamazepine (Tegretol) (121-123)

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There are two main types of such inhibitors, SAH (Zweygarth et al., 1986) (Table 1

Lenth, R