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A different model was proposed based on differential -catenin binding affinity by unphosphorylated versus phosphorylated APC (Ha et al., 2004)
Journal of Biological Chemistry , 1978
doi: 10.1038/nmicrobiol.2016.26 152 SavoldiA.CarraraE.GrahamD
Cell Commun Signal 22:163
Furthermore, PPI and related saponins exert antitumor effects through ROS-mediated mechanisms, suppressing proliferation, inducing apoptosis, and reversing multidrug resistance in lung, breast, colorectal, and hepatocellular carcinomas
