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In EAAC1 KO mice, however, 50 mg/kg dose did not produce meaningful behavioral improvement, prompting us to compare higher doses

In addition, pharmacogenomics studies could be useful in the identification of mutations in genes influencing antitumor drug metabolism, and this could also be an important source of data for optimal dosing of these drugs in patients [101]

Ferroptosis interaction with inflammatory microenvironments: Mechanism, biology, and treatment

[DOI] [PMC free article] [PubMed] [Google Scholar] 254.Stresser D.M., Kopec A.K., Hewitt P., Hardwick R.N., Van Vleet T.R., Mahalingaiah P.K.S., OConnell D., Jenkins G.J., David R., Graham J., et al

Sex-Related Differences in Mouse Renal Metabolism and Toxicity of Acetaminophen