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Description
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If side effects become intolerable at any dose level, dropping back to the previous dose for two to four additional weeks before attempting escalation again often allows successful progression

Strategic approaches can support optimal levels

For example, a multifunctional nanoformulation (Rapa@DAK/siRNA) was developed, combining rapamycin, BACE1 siRNA, and the A-targeting KLVFF peptide

R.LutzC
