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VEGF blocks Notch signaling and enhance sprouting, branching, migratory capacity and filopodia formation in tip cells [13]

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The less diverse cell death signaling network in erythrocytes is associated primarily with expulsion of their organelles during maturation and makes Ca 2+ signaling a master regulator of eryptosis, while the caspase-dependent apoptotic machinery is more sophisticated and redundant

That matters because connective tissues remodel slowly