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Description
The STEP UP trial, published in The Lancet Diabetes & Endocrinology in September 2025, showed 18.7% average weight loss at 72 weeks compared to 15.6% at the standard 2.4 mg dose
Clinically, this matters because chronic migraine is not defined by one dramatic headache
Most patients experience nausea within 24 to 72 hours of their first injection
Phone support is available and responsive
5 mg Vial Reconstitution: Add 2.0 mL bacteriostatic water 2.5 mg/mL concentration
