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High standards of cleanliness and precision are maintained to prevent contamination

Across major clinical trials (LEADER, REWIND, SUSTAIN, SURPASS), no increase in MTC incidence has been observed, and human C-cells express very low levels of GLP-1 receptors

Conclusions GLP-1 RAs produce modest but consistent reductions in BP, typically in the range of 2-5 mm Hg systolic, with the largest effects seen in agents associated with greater weight loss

Electrolyte supplementation can help, especially during the first few weeks

Additional Health Benefits Like the injectable version, the Wegovy pill is also FDA-approved to reduce the risk of major adverse cardiovascular events , including cardiovascular death, nonfatal heart attack, or nonfatal stroke, in adults with established cardiovascular disease and obesity or elevated body weight