glp 1 agonist and alcohol use disorder GLP-1 RAs may reduce alcohol-related hospitalization risk Repurposing GLP-1 receptor agonists for

At lower doses, receptor activation may still occur, but the strength and consistency of appetite suppression have not been defined in controlled trials

95% CI 0.23, 0.33), and GLP-1 Ras/metformin (WMD: 0.27

As mentioned, a secondary analysis of an RCT assessing the cardiometabolic effects of exenatide in 40 people with schizophrenia 140 also looked at measures of cognition and psychosocial functioning (that is, Brief Assessment of Cognition in Schizophrenia, ReyOsterreith Complex Figure Test, Short-Form Health Survey, Personal and Social Performance Scale, Positive and Negative Syndrome Scale), but found no effect for this GLP-1RA compared with placebo over 3 months 133

An early study of [dPhe4]glucagon demonstrates a 655% improvement in hepatic glucose production potency over that of native glucagon during a 2-hr span [172]

Accessed May 1, 2025